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S4 Biology: Cellular Respiration Paper 1 (Foundation)

S4 Biology: Cellular Respiration Paper 1 (Foundation)

  • 2026-11-03

S · 4

S4 Biology: Cellular Respiration Paper 1 (Foundation)

Read whether each item asks for a location, a product or a quantity. This paper covers the equation, stage locations and anaerobic products.

Quick answer 1. 12 O2, 12 CO2 | 2. cytoplasm / matrix / inner membrane | 3. lactate | 4. ethanol and CO2 | 5. 6.7% | 6. RQ 1.0 | 7. +50% | 8. 120 cm3 | 9. 7.2 cm3 | 10. glycolysis still gives 2 ATP

01 Paper details (check answers afterwards)

Item Detail
Questions 10 questions
Suggested time 25 minutes
Difficulty mix Foundation 4 · Intermediate 3 · Challenge 2 · Error redo 1
Chapter Chapter: S4 Biology — Cellular Respiration
Level Foundation

02 Questions (10 items)

  1. FoundationComplete oxidation of 2 glucose molecules needs how many oxygen molecules and releases how many carbon dioxide molecules?
  2. FoundationWhere in the cell do glycolysis, the Krebs cycle and the electron transport chain take place?
  3. FoundationWhen human muscle runs short of oxygen during hard exercise, glucose is broken down into what?
  4. FoundationWhich two substances does yeast produce when it breaks down glucose without oxygen?
  5. IntermediateAerobic respiration yields a net 30 ATP per glucose, of which glycolysis gives a net 2. What percentage comes from glycolysis (1 d.p.)?
  6. IntermediateA tissue uses 400 cm3 of oxygen and releases 400 cm3 of carbon dioxide in 10 minutes. What is its respiratory quotient and main substrate?
  7. IntermediateThe same tissue produces 24 bubbles per minute at 25 C and 36 at 35 C. By what percentage does the rate rise?
  8. ChallengeFermentation uses 0.90 g of glucose (Mr 180). At a molar volume of 24.0 dm3/mol, what is the maximum volume of carbon dioxide in cm3?
  9. ChallengeA 0.50 g sample uses 1.2 cm3 of oxygen in 20 minutes. Find the oxygen uptake per gram per hour.
  10. Error redoA student claims anaerobic respiration produces no ATP at all. Where is the error?

03 Answers and one-line notes

# Answer One-line note
1 It needs 12 oxygen molecules and releases 12 carbon dioxide molecules. Each glucose molecule uses exactly six oxygen molecules and releases six carbon dioxide molecules.
2 Glycolysis in the cytoplasm, the Krebs cycle in the mitochondrial matrix, the chain on the inner membrane. Location fixes the hydrogen route, which explains why only glycolysis survives without oxygen.
3 It is converted into lactate. Accumulated lactate causes fatigue and still needs oxygen afterwards.
4 It produces ethanol and carbon dioxide. This is exactly the basis of brewing and bread making.
5 It accounts for 6.7%. Percentage = 2 / 30 x 100; the rest comes from oxidative phosphorylation.
6 RQ = 1.0, so the main substrate is carbohydrate. The respiratory quotient of carbohydrate is close to 1.0.
7 It rises by 50.0%. Rise = (36 – 24) / 24 x 100.
8 That is 0.005 mol of glucose, giving 120 cm3 of carbon dioxide. Find moles from mass first, then multiply by molar volume to get cm3.
9 It is 7.2 cm3 per gram per hour. Convert 20 minutes to one hour first, then scale by mass.
10 Glycolysis still gives a net 2 ATP; only the large output of the chain is missing. Anaerobic yield is small but never zero.

04 What to do after marking

  • After marking, redo only the wrong items and write down which step went wrong (formula, unit, or misread number).
  • Repeat the same item two days later; move to the next paper only when both attempts are correct.
  • Parents only need the answer and note columns; there is no need to explain every item.

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