IGCSE Biology Past Papers & Drilling (Paper 3): Enzymes, Circulation, Excretion
- 2026-10-13
TUTORZONE ORIGINAL DRILLING MOCK · CAMBRIDGE IGCSE BIOLOGY (0610) PAPER 3
Written to the Cambridge 0610 syllabus: Paper 3 Theory (Core), 80 marks, 1 h 15 min, 50% (short-answer and structured); plus Paper 1 Multiple Choice (Core, 40 marks, 30%). This is a Paper 3 drilling mock: 6 questions for 80 marks with answers and techniques.
What is in IGCSE Biology (0610) Paper 3?
Direct answer: Paper 3 Theory (Core), 80 marks, 1 h 15 min, 50% (short-answer and structured).

Assessment at a glance (2027)
| Component | Content | Weighting | Duration |
|---|---|---|---|
| Paper 3 (Theory, Core) | Short-answer and structured, 80 marks | 50% | 1 h 15 min |
| Paper 1 (Multiple Choice, Core) | 40 four-option items, 40 marks | 30% | 45 min |
IGCSE Biology Paper 3 drilling technique: function answers pair structure with function; enzyme answers must say denatured; circulation answers give the pulmonary and systemic routes; explain food-chain limits with the 10% energy rule.
How this paper was built
This is a TutorZone original drilling mock: the questions follow the Cambridge 0610 structure (Paper 3 Core, 80 marks, 50%) and the answers are our own, not Cambridge past papers or marking references.
Pacing
| Section | Marks | Suggested time | What to do first |
|---|---|---|---|
| Paper 3 (Theory, Core) | 50% | about 9 min per question | functions + processes + diagrams |
| Paper 1 (Multiple Choice, Core) | 30% | about 68 s per question | core content only |
Why do food chains rarely exceed four to five levels?
Direct answer: only about 10% of energy passes to each next level, the rest being lost to respiration, heat and waste.
Paper 3: core theory drilling (6 questions, 80 marks)
Say denatured for enzymes; know the circulation routes.
Question 1 (14 marks)
State the functions of the nucleus, cytoplasm and cell membrane, and say which are found in both plant and animal cells.
Question 2 (13 marks)
Explain why a very high temperature permanently destroys an enzyme.
Question 3 (13 marks)
State the functions of the three main nutrients in a balanced diet.
Question 4 (13 marks)
Describe the paths of the systemic and pulmonary circulations in humans.
Question 5 (13 marks)
State two functions of the kidney in excretion and fluid balance.
Question 6 (14 marks)
Explain why food chains rarely have more than four or five trophic levels.
Why is an enzyme permanently destroyed by high temperature?
Direct answer: the heat destroys the shape of the active site (denaturation), so the substrate can no longer bind.
Paper 3 answers
Question 1
The nucleus controls the cell and holds the genetic material (5); the cytoplasm is where reactions occur (5); the membrane controls what enters and leaves (4) – all three occur in both plant and animal cells.
Question 2
High temperature destroys the shape of the active site (denaturation) (7), so the substrate can no longer bind and the reaction stops (6).
Question 3
Carbohydrates supply energy (5); proteins for growth and repair (4); fats store energy and insulate (4).
Question 4
Pulmonary: right ventricle -> pulmonary artery -> lungs -> pulmonary vein -> left atrium (7). Systemic: left ventricle -> aorta -> body -> vena cava -> right atrium (6).
Question 5
(1) Removes nitrogenous waste such as urea (forming urine) (7). (2) Regulates water and salt balance (6).
Question 6
Only about 10% of energy passes to each next level (7), the rest being lost in respiration, heat and waste, too little to support more levels (7).
Which topics does this paper drill?
Direct answer: cell functions, enzyme denaturation, balanced diet, circulation, kidney excretion and food-chain energy.
Where these marks are usually lost
| Mistake | What it looks like | What it costs | Instead |
|---|---|---|---|
| Enzyme as stopped | Just stops | Say denatured | denatured |
| Circulation direction | Pulmonary vein to right atrium | Pulmonary vein to left atrium | left atrium |
| Food chain unexplained | Just too short | Explain the 10% energy loss | 10% rule |
How to use this paper
First drill: the full 1 h 15 min on all 6 questions with no references.
Mark it: check the structure-function pairs and process order.
Second drill: redo three to seven days later, aiming to finish inside 1 hour.
What should I do after drilling this paper?
Direct answer: log answers missing denaturation or with wrong directions; redo in three to seven days; and drill Paper 4 (Extended theory).
FAQ
Is this a Cambridge past paper?
No. The questions and answers are TutorZone originals, not Cambridge past papers or marking references.
What is in IGCSE Biology Paper 3?
Theory (Core), 80 marks, 1 h 15 min, 50%, short-answer and structured questions.
Why do food chains rarely exceed four to five levels?
Only about 10% of energy passes to each next level, the rest being lost.
Official references
| Resource | What to check |
|---|---|
| Cambridge IGCSE Biology 0610 page | Confirm the paper marks and times |
| https://www.tutorzone.com.hk/en-igcse-biology-0610-paper-1-mock-2027/ | IGCSE Biology Paper 1 drilling mock |
Related: practice area · IGCSE Biology Paper 2 drilling mock
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